Associate Professor of Biological Sciences
Jinsil Kim’s teaching interests are in the areas of cell biology and immunology. She teaches upper division biology courses for students majoring in Biological Sciences and related science majors. Kim comes to Biola from the National Institutes of Health (NIH) and has a research background encompassing a wide variety of fields, including cell and molecular biology, genetics, developmental biology, and human diseases. Students may participate in research with her through BIOS 450 Directed Research or at other institutions through BIOS 480 Internship.
Kim’s primary research interest lies in the area of RNA biology, particularly splicing. The goal of her research is twofold: to elucidate how the process of alternative splicing is regulated and to understand how aberrant alternative splicing contributes to disease. Her current focus is on investigating the regulatory role of RNA binding proteins in alternative splicing and identifying splicing signatures associated with immune dysfunction and neurological disorders. Her research utilizes mammalian cells as an experimental system, and employs a combination of microscopy, biochemical, genomic, and molecular biology approaches to delineate how RNA regulatory networks influence normal cellular functions and pathological processes. Kim conducted post-doctoral research at NIH, UCLA, and the University of Rochester.
"Gene deletion by synthesis in yeast" Kim, J., Kim, D. U., and Hoe, K. L., Methods in Molecular Biology, 2017.
"Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the accumulation and functional activity of myeloid-derived suppressor cells (MDSCs) in pancreatic cancer," Song, J., Lee, J., Kim, J., Jo, S., Kim, Y. J., Baek, J. E., Kwon, E.-S., Lee, K.-P., Yang, S.,
Kwon, K.-S., Kim, D.-U., Kang, T. H., Park, Y.-Y., Chang, S., Cho, H.-J., Kim, S. C., Koh, S. S.,
and Kim, S., Oncotarget 7, 2016 2016.
"Identification of Rbd2 as a candidate protease for sterol regulatory element binding protein (SREBP) cleavage in fission yeast," Kim, J., Ha, H. J., Kim, S., Choi, A. R., Lee, S. J., Hoe, K. L., and Kim, D. U., Biochemical and Biophysical Research Communications 468, 2015.
"Isolation and culture of murine primary chondrocytes," Mirando, A. J., Dong, Y., Kim, J., and Hilton, M. J., Methods in Molecular Biology 1130, 2014.
"Sequence variants in oxytocin pathway genes and preterm birth: a candidate gene association study," Kim, J., Stirling, K. J., Cooper, M. E., Ascoli, M., Momany, A. M., McDonald, E. L., Ryckman, K. K., Rhea, L., Schaa, K. L., Cosentino, V., Gadow, E., Saleme, C., Shi, M., Hallman, M., Plunkett, J., Teramo, K. A., Muglia, L. J., Feenstra, B., Geller, F., Boyd, H. A., Melbye, M., Marazita, M. L., Dagle, J. M., and Murray, J. C, BMC Medical Genetics, 2013.
"Genome-wide analysis of DNA methylation in human amnion," Kim, J., Pitlick, M. M., Christine, P. J., Schaefer, A. R., Saleme, C., Comas, B., Cosentino, V., Gadow, E., and Murray, J. C, The Scientific World Journal, 2013.
"Transcriptome landscape of the human placenta," Kim, J., Zhao, K., Jiang, P., Lu, Z., Wang, J., Murray, J. C., and Xing, Y., BMC Genomics 13, 2012.
"A modified Sleeping Beauty transposon system that can be used to model a wide variety of human cancers in mice," Dupuy, A. J., Rogers, L. M., Kim, J., Nannapaneni, K., Starr, T. K., Liu, P., Largaespada, D. A., Scheetz, T. E., Jenkins, N. A., and Copeland, N. G., Cancer Research 69, 2009.
The 60th annual American Society of Human Genetics meeting,
Washington, DC. Presented on "Genome-wide transcriptome analysis of human placenta." 2010.
The 59th annual American Society of Human Genetics meeting, Honolulu, HI. Presented on "SNP and expression analyses of candidate genes for orofacial clefts." 2009.
The 59th annual American Society of Human Genetics meeting and the Society of Craniofacial Genetics Meeting, Honolulu, HI. Presented on "Variation in FGFR2 expression correlates with genotype at SNPs associated with nonsyndromic cleft lip/palate and breast cancer." 2009.
Idaho State University Undergraduate Research Symposium in conjunction with the Idaho Academy of Science Annual Meeting, Pocatello, ID. Presented on "Effect(s) of thalidomide on angiogenesis during limb development." 2004.
The second annual Idaho Biomedical Research Infrastructure Network (BRIN) Research Conference, Boise, ID. Presented on "Contrasting patterns of molecular variation in mitochondrial and nuclear genes: an examination of phenotypic variation in external male genitalia." 2003.
Biola University